So you have to make a backup of your Mac and included all the apps, profiles etc. Your options are really Time Machine backup or a clone software. We take it you have a hard rive to use as the backup of the said device you require a backup of. The answer is also a little bit more complicated as what state the Mac is in, is the machine running an encrypted drive, is the drive removable, does the Mac boot etc. All valid questions.
For the drive removal option you can take out the drive place in an adaptor and plug into another machine and run one of the backup software solutions to get your backup. Sound simple and it is if you can get access to the drive hardware easily have the correct adapter to plug the drive in to a spare machine to do the backup.
